738: Placental 11b-HSD2 and cardiometabolic heath indices in infancy
نویسندگان
چکیده
منابع مشابه
CLINICAL STUDY Course of placental 11b-hydroxysteroid dehydrogenase type 2 and 15-hydroxyprostaglandin dehydrogenase mRNA expression during human gestation
Background: During human pregnancy, 11b-hydroxysteroid dehydrogenase type 2 (11b-HSD2) plays an important role in protecting the fetus from high maternal glucocorticoid concentrations by converting cortisol to inactive cortisone. Furthermore, 11b-HSD2 is indirectly involved in the regulation of the prostaglandin inactivating enzyme 15-hydroxyprostaglandin dehydrogenase (PGDH), because cortisol ...
متن کاملA 738
New nonlinear FETI-DP (dual-primal finite element tearing and interconnecting) and BDDC (balancing domain decomposition by constraints) domain decomposition methods are introduced. In all these methods, in each iteration, local nonlinear problems are solved on the subdomains. The new approaches can significantly reduce communication and show a significantly improved performance, especially for ...
متن کاملAnthropometric indices, cord length and placental weight in newborns.
A study on the anthropometric indices of 3835 singleton newborn babies was conducted over a four months period at Sree Avittom Thirunal Hospital, Trivandrum. Of these, 1921 (50.1%) were male babies and 1914 (49.9%) were female babies. The majority of infants (43%) were born to the middle socio-economic groups and the mean birth weight of babies was high among the high-income groups. Five hundre...
متن کاملAppropriate anthropometric indices to identify cardiometabolic risk in South Asians.
BACKGROUND South Asians show an elevated cardiometabolic risk compared to Caucasians. They are clinically metabolically obese but are considered normal weight based on current international cut-off levels of several anthropometric indices. This study has two main objectives: (i) to predict the most sensitive anthropometric measures for commonly studied cardiometabolic risk factors, and (ii) to ...
متن کاملMaternal Prenatal Mental Health and Placental 11β-HSD2 Gene Expression: Initial Findings from the Mercy Pregnancy and Emotional Wellbeing Study
High intrauterine cortisol exposure can inhibit fetal growth and have programming effects for the child's subsequent stress reactivity. Placental 11beta-hydroxysteroid dehydrogenase (11β-HSD2) limits the amount of maternal cortisol transferred to the fetus. However, the relationship between maternal psychopathology and 11β-HSD2 remains poorly defined. This study examined the effect of maternal ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: American Journal of Obstetrics and Gynecology
سال: 2019
ISSN: 0002-9378
DOI: 10.1016/j.ajog.2018.11.761